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This whitepaper reports on the use of μPAC™ in combination with MS for the characterisation of HCPs and their monitoring during downstream processing.
Industry experts share their latest research and developments in pharma.
Discover the new µPAC™ C18 capLC column (1 – 15 µl/min) with unrivalled separation power and plug and play connectivity.
The practice of bottom-up proteomics relies to a large extent on the separation performance that can be achieved with state-of-the art nano LC-MS/MS equipment.
PharmaFluidics NV is a game-changing innovator in the field of analytical chromatography. The company has devised a fundamentally new way of performing separations by creating nano-LC columns on a silicon chip...
The use of micro pillar array columns (μPAC™) for characterising antibody-drug conjugates is presented. Kadcyla® (ado-trastuzumab emtansine) and, for comparison, Herceptin® (trastuzumab) tryptic digests were analysed on a 200 cm μPAC™ C18 column and peaks eluting were detected by ultraviolet (UV) spectroscopy and high-resolution mass spectrometry (MS).
PharmaFluidics will attend the 47th International Symposium on High Performance Liquid Phase Separations and Related Techniques on the 29 July to 02 August in Washington, DC.
