Patch clamp electrophysiology steps up a gear
20 May 2005 | By Derek J. Trezise, Assay Development & Compound Profiling, GlaxoSmithKline Research & Development
The advent of higher throughput patch clamp electrophysiology systems has begun to change the face of ion channel drug discovery. Systems such as IonWorksHT, PatchXpress and QPatch should allow electrophysiology to be re-positioned from an occasional reagent and compound ‘spot-check’ method, to a frontline gene expression analysis tool and drug…