Application note

Application note: Isokinetic microbial air sampling on MAS-100 instruments

Microbial air sampling in controlled environments should be performed isokinetically. The following text explains the isokinetic sampling process using MAS-100 instruments with a flow rate of 100 L/min and compares it with sampling at a lower flow rate of 25 L/min.

MICROBIAL AIR SAMPLING in low turbulence unidirectional airflow environments (cleanrooms, isolators, RABS and other controlled environments) should be performed with minimal interference between the sampling process and the surrounding airflow. The fact that EU GMP Annex 1 requests isokinetic sampling for total particles (§5.9, EU GMP Annex 1) further strengthens the importance of collecting particles from the air over a defined time and area without disturbing the air path.

Download this application note to discover more about:

  • The calculation of isokinetic sampling speed
  • CFD simulation of isokinetic sampling speed
  • Schematic representation of different sampling modes regarding isokinesis
  • A laminar flow study.

 

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