Whitepapers/App Notes/Posters

Whitepaper: Beta-glucans in purified water – do they really cause overestimation of endotoxin values?

Posted: 14 December 2020 | | No comments yet

Over the last century, the bacterial endotoxin test (BET) has evolved to keep pace with modern technology and lab expectations: from rabbit pyrogen testing to Limulus amebocyte lysate (LAL), to current developments with recombinant horseshoe crab coagulation factors.

The advancement of process and product testing methodology has been historically important as they benefit patient safety and can result in sustainable and non-inferior testing capacity. There are currently three commercially available recombinant Factor C (rFC) reagents and a fully recombinant LAL (rLAL) in development by Charles River. Global compendia’s current position is that recombinant LAL requires validation as an alternative method.

    To read this whitepaper in full, please complete the form below:

     









    This specialist content is provided to you free-of-charge thanks to the kind support of Charles River

    By clicking submit you confirm that you accept our terms and conditions and privacy policy.

    Related topics

    Related organisations

    Leave a Reply

    Your email address will not be published. Required fields are marked *